LYS-16

LYS-16 designates a specific stereoisomer and position within a peptide or protein sequence. Specifically, it refers to the amino acid Lysine (Lys, K) located at the 16th position in the amino acid sequence of a polypeptide chain.

In protein nomenclature, individual amino acids within a sequence are often identified using a three-letter code, a single-letter code, and their position number. Therefore, LYS-16 indicates that the amino acid at position 16 is the amino acid Lysine.

The properties of Lysine, such as its positive charge at physiological pH due to its epsilon-amino group, will influence the overall structure and function of the protein. The position of Lysine at the 16th residue is important because the surrounding amino acids and the overall protein structure will determine the role of this specific Lysine residue in protein folding, stability, interactions with other molecules (such as DNA, RNA, or other proteins), and catalytic activity (if the protein is an enzyme). Post-translational modifications can also occur at the Lysine residue, further altering its chemical properties and influencing protein function. For example, acetylation or methylation of the epsilon-amino group can neutralize the positive charge, affecting protein-protein interactions and chromatin structure, respectively. The accessibility and reactivity of the LYS-16 residue depends on its context within the three-dimensional structure of the protein.