Ann Clarke (immunologist)

Ann Clarke is an immunologist known for her research on systemic lupus erythematosus (SLE), also known as lupus. Her work has focused on the genetic and environmental factors that contribute to the development and progression of this autoimmune disease. Specifically, Dr. Clarke has extensively studied the role of autoantibodies, particularly anti-dsDNA antibodies, in lupus pathogenesis, as well as the influence of interferon signaling and B cell activation.

Dr. Clarke's research also includes studies on the epidemiology of SLE, examining its prevalence, incidence, and risk factors within diverse populations. This research aims to understand the geographic and ethnic variations in lupus susceptibility and severity.

She has contributed significantly to the understanding of lupus through various publications and presentations, and has participated in collaborative studies aimed at developing improved diagnostic and therapeutic strategies for lupus patients. Her research often integrates clinical observations with laboratory findings to translate basic science discoveries into tangible benefits for those living with SLE.