TRERF1

TRERF1, or Transcriptional Regulator Enhancer Factor 1, is a protein encoded by the TRERF1 gene in humans. It functions as a transcriptional repressor or activator, depending on the cellular context and the specific target gene.

TRERF1 is involved in a variety of cellular processes, including cell growth, differentiation, and apoptosis. Research suggests it plays a role in the development and progression of several types of cancer. It interacts with other proteins to regulate gene expression by binding to specific DNA sequences in the promoter regions of target genes. The protein's activity can be modulated by post-translational modifications such as phosphorylation and acetylation. Understanding the precise mechanisms by which TRERF1 regulates gene expression is an ongoing area of research.