SLC35C2

SLC35C2 is a human gene encoding a protein belonging to the solute carrier family 35 (SLC35). Proteins in this family are transmembrane transporters involved in the transport of various nucleotide sugars. Nucleotide sugars are essential precursors for glycosylation, a process critical for the synthesis of glycoproteins, glycolipids, and proteoglycans. These molecules are involved in a wide range of cellular processes, including cell signaling, cell adhesion, and protein folding.

The precise substrate specificity of the SLC35C2 transporter remains under investigation, although it is understood to be involved in the transport of nucleotide sugars across the Golgi membrane. This transport is crucial because nucleotide sugars are synthesized in the cytoplasm but are utilized within the Golgi apparatus for glycosylation reactions.

Mutations or dysregulation in SLC35C2 have been implicated in certain diseases and developmental disorders, often affecting glycosylation pathways. Research continues to explore the specific roles and clinical significance of SLC35C2 in human health and disease. Further research is needed to fully elucidate its function and involvement in specific metabolic pathways and diseases.