Jan Schouten (geneticist)

Jan Schouten is a Dutch geneticist known for his contributions to the fields of genomics and molecular diagnostics. His research has focused on developing and applying innovative molecular techniques for detecting and characterizing genetic variations in human disease, particularly in the context of cancer and prenatal diagnostics.

Schouten's work has involved the development and application of technologies such as multiplex ligation-dependent probe amplification (MLPA) and array comparative genomic hybridization (array CGH) to detect gene copy number variations and chromosomal abnormalities. These techniques have proven invaluable in identifying genetic drivers of cancer and in improving the accuracy of prenatal screening for chromosomal disorders.

Furthermore, Dr. Schouten's research has extended to the development of new methods for single-cell genomics, enabling the analysis of genetic heterogeneity within individual cells and tissues. This approach has provided valuable insights into the clonal evolution of tumors and the mechanisms of drug resistance.

His publications and presentations have contributed significantly to the understanding of the genetic basis of various diseases, and his research has had a direct impact on clinical practice, leading to improved diagnostic and therapeutic strategies.