PSORTdb

PSORTdb is a database dedicated to the prediction and analysis of protein subcellular localization in prokaryotic organisms. It provides experimentally validated and predicted protein localization data, along with various computational tools to assist researchers in determining where a protein resides within a bacterial or archaeal cell. This information is crucial for understanding protein function and cellular processes.

PSORTdb integrates information from various sources, including experimentally determined protein localization data derived from literature curation and large-scale experimental studies. It also incorporates predictions generated by various computational algorithms designed to identify localization signals, transmembrane domains, and other features associated with specific subcellular compartments.

The database allows users to search for proteins based on various criteria, such as protein name, sequence, organism, and predicted or experimental localization. Search results provide information about the protein's sequence, predicted localization probabilities for different subcellular compartments (e.g., cytoplasmic membrane, periplasm, outer membrane, extracellular), supporting evidence (e.g., homology to proteins with known localization, presence of signal peptides), and links to relevant literature and other databases.

PSORTdb aims to provide a comprehensive and reliable resource for researchers studying bacterial and archaeal cell biology, protein function, and drug target identification. The database is continually updated with new data and improved prediction algorithms to enhance its accuracy and utility.