Neoflavan

Neoflavans are a class of flavonoids, a group of plant secondary metabolites known for their antioxidant and various biological activities. Chemically, they are characterized by having a 4-arylchromane skeleton, distinguishing them from other flavonoids where the aryl group is attached at the 2 or 3 position of the chromane ring.

Neoflavans are relatively rare compared to other flavonoid classes. They are found in limited plant species and are biosynthesized through a different pathway than the more common flavonoids. Their biosynthesis involves the enzyme chalcone isomerase, which catalyzes the formation of a neoflavan precursor.

Structurally, neoflavans exhibit diverse substitution patterns, leading to a variety of compounds with distinct properties. Some neoflavans are known for their potential medicinal applications, including anti-inflammatory, anticancer, and antimicrobial activities, although research in these areas is ongoing. Their specific effects depend on their chemical structure and the biological systems in which they are tested. Due to their structural similarity to isoflavonoids, discerning between the two can sometimes require advanced analytical techniques.