Nat Exon

A "Nat Exon," in the context of genomics and bioinformatics, typically refers to a naturally occurring exon within a gene. An exon is a segment of a DNA or RNA molecule containing information coding for protein or RNA sequence.

In eukaryotic genes, the coding regions (exons) are interrupted by non-coding regions (introns). During gene expression, the pre-mRNA molecule undergoes splicing, a process where introns are removed and exons are joined together to form the mature mRNA transcript.

Therefore, a "Nat Exon" distinguishes itself from synthetic exons or exons that have been artificially engineered or modified. It is the exon as it exists in the original, unmodified gene sequence found in nature. Understanding the sequence and structure of natural exons is crucial for studying gene function, regulation, and evolution, as well as for identifying mutations and variations that may contribute to disease.