HU-210

HU-210, also known as 1,1-Dimethylheptyl-delta8-tetrahydrocannabinol, is a synthetic cannabinoid approximately 100 to 800 times more potent than naturally occurring delta-9-tetrahydrocannabinol (THC), the primary psychoactive component of cannabis. It is a structural analog of THC, featuring a dimethylheptyl side chain instead of THC's pentyl side chain.

HU-210 binds to both CB1 and CB2 cannabinoid receptors in the brain and throughout the body, leading to profound psychoactive effects. Due to its extreme potency, its use is associated with a significant risk of adverse effects, including severe anxiety, paranoia, psychosis, hallucinations, nausea, vomiting, and cardiovascular complications. Accidental or intentional overdose can be dangerous and require medical attention.

While HU-210 has been used in research to study the cannabinoid system, it is not approved for medical use in most jurisdictions due to its high potency and potential for severe side effects. It is often encountered as a synthetic cannabinoid found in "spice" or "K2" products, which are often marketed as legal alternatives to cannabis. The unregulated nature of these products, combined with the unknown quantities of HU-210 or similar compounds they contain, makes their consumption particularly hazardous.

The "HU" designation in its name indicates that it was synthesized at the Hebrew University (HU) of Jerusalem.