FAB-144
FAB-144 is a synthetic cannabinoid that mimics the effects of tetrahydrocannabinol (THC), the psychoactive component of cannabis. It is a relatively new compound and is not well-studied, but it has been identified in "spice" or "herbal incense" products. These products are often marketed as legal alternatives to cannabis, but they can contain a variety of synthetic cannabinoids, often with unpredictable and potentially dangerous effects.
FAB-144 binds to the CB1 and CB2 cannabinoid receptors in the brain and body. The CB1 receptor is primarily responsible for the psychoactive effects, while the CB2 receptor is involved in immune system modulation.
The use of FAB-144 and other synthetic cannabinoids has been linked to a range of adverse health effects, including:
- Anxiety and paranoia
- Hallucinations
- Nausea and vomiting
- Seizures
- Tachycardia (rapid heart rate)
- Hypertension (high blood pressure)
- Loss of consciousness
- Kidney damage
- In some cases, death
Because FAB-144 is often found in unregulated products, the actual dose and purity can vary significantly, making it difficult for users to predict the effects. Its legal status varies by jurisdiction; it may be controlled or prohibited in some regions due to its potential for abuse and adverse health effects. Due to its relatively recent emergence, FAB-144 may not be explicitly listed in controlled substance lists in some locations but may fall under broader laws prohibiting the sale and possession of substances with similar chemical structures and psychoactive effects.