CTNNAL1

CTNNAL1, also known as Catenin Alpha Like 1, is a protein encoded by the CTNNAL1 gene in humans. It is a member of the alpha-catenin family of proteins. Alpha-catenins are known to play a crucial role in cell adhesion and cytoskeletal organization, acting as links between cadherins (transmembrane proteins that mediate cell-cell adhesion) and the actin cytoskeleton.

The precise function of CTNNAL1 is not fully understood, and research is ongoing to elucidate its specific role in cellular processes. It is believed to be involved in the regulation of cell-cell adhesion and the maintenance of epithelial integrity. Like other alpha-catenins, it likely interacts with cadherins and actin filaments, contributing to the formation and stabilization of adherens junctions.

Adherens junctions are essential for maintaining tissue architecture, cell signaling, and embryonic development. Disruptions in adherens junction function have been implicated in various diseases, including cancer metastasis. Therefore, understanding the role of CTNNAL1 in these processes is of significant interest.

Studies suggest that CTNNAL1 may have tissue-specific functions, with varying levels of expression in different tissues. Further research is needed to determine the specific roles of CTNNAL1 in different cellular contexts and its potential involvement in disease pathogenesis. Gene expression studies and protein interaction analyses are being used to further understand the function of CTNNAL1.