Aquasome

An aquasome is a three-dimensional self-assembling structure composed of pharmaceutical drug molecules adsorbed on a solid nanocrystalline core coated with a polyhydroxy oligomer film. Primarily used in drug delivery systems, aquasomes are biologically compatible and structurally similar to naturally occurring biological substances. The core, typically ceramic in nature, provides structural integrity, while the polyhydroxy oligomer film (commonly cellobiose or other sugars) protects and stabilizes the encapsulated drug, allowing for controlled release and enhanced bioavailability. The "aqua" portion of the name refers to the high water content within the structure, which preserves the native conformation and biological activity of the encapsulated molecules, particularly proteins and peptides. Aquasomes are considered an advanced drug delivery vehicle for proteins, peptides, enzymes, hormones, vaccines, and genes. The method allows drugs to be delivered to targeted sites in the body and is less harsh than other traditional drug delivery methods.