Pyrvinium

Pyrvinium is an anthelmintic medication primarily used to treat pinworm (enterobiasis) infections. It is available under various brand names.

Mechanism of Action: Pyrvinium works by inhibiting glucose uptake by the pinworms, effectively starving them. It is believed to also interfere with the parasites' oxygen consumption. Pyrvinium acts locally in the gastrointestinal tract, with minimal absorption into the bloodstream.

Indications: The primary indication for pyrvinium is the treatment of pinworm infections. It is generally administered as a single dose.

Administration: Pyrvinium is typically taken orally, usually in the form of tablets or suspension. It is important to follow the dosage instructions provided by a healthcare professional or as indicated on the product label. It may be taken with or without food.

Adverse Effects: Common side effects of pyrvinium include nausea, vomiting, abdominal cramps, and diarrhea. A notable side effect is that it can turn the stool red, which is normal and temporary. Less common side effects may include photosensitivity.

Contraindications and Precautions: Pyrvinium is contraindicated in individuals with known hypersensitivity to pyrvinium or any of the excipients. Caution is advised in patients with inflammatory bowel disease or other gastrointestinal conditions.

Drug Interactions: Significant drug interactions with pyrvinium are not well documented, but it's important to inform your healthcare provider of all medications you are taking.

Pregnancy and Lactation: The use of pyrvinium during pregnancy and lactation should be discussed with a healthcare professional to weigh the potential benefits against the potential risks.

Storage: Pyrvinium should be stored according to the instructions provided on the product packaging, typically at room temperature and away from moisture and light.