PPP1R9A

PPP1R9A, also known as Inhibitor-1 interacting protein, is a human gene that encodes a protein involved in the regulation of protein phosphatase 1 (PP1). This protein is a regulator of PP1 activity, modulating its involvement in various cellular processes, including glycogen metabolism, cell cycle progression, and muscle contraction.

The PPP1R9A gene is located on chromosome 19q13.2. The protein product of the PPP1R9A gene interacts directly with PP1, preventing its interaction with other substrates. This inhibitory action is modulated by phosphorylation events.

The specific function of PPP1R9A is still being investigated, but research suggests it plays a crucial role in controlling the activity of PP1 in particular cellular contexts. Disruptions or mutations affecting the PPP1R9A gene and its protein product may contribute to irregularities in the biological pathways regulated by PP1. Its role in signal transduction and metabolic regulation is an area of active research.