Edward Roberts (chemist)

Edward Roberts was an American chemist best known for his work in the field of enzyme kinetics and mechanism, particularly his investigations into the enzyme lysozyme. He made significant contributions to understanding the catalytic activity of this enzyme and the factors that influence its function.

Roberts' research focused on elucidating the detailed steps involved in the lysozyme-catalyzed hydrolysis of polysaccharides. He employed a variety of techniques, including steady-state kinetics, pre-steady-state kinetics, and site-directed mutagenesis, to probe the enzyme's active site and identify key amino acid residues involved in substrate binding and catalysis. His studies provided valuable insights into the role of specific amino acids in stabilizing the transition state and facilitating bond cleavage.

His work helped to refine the understanding of enzyme mechanisms in general and provided a detailed model for lysozyme's mode of action. His publications are considered foundational contributions to the field of enzymology. Specific details of his academic career and affiliations remain relatively obscure, though his research output and publications demonstrate his expertise and impact.