Richard Cotton (geneticist)

Richard Cotton is an Australian human geneticist known for his contributions to the field of mutation detection and genetic variation. He is best known for his work in developing methods for identifying mutations in DNA, particularly in the context of inherited diseases and cancer.

Cotton founded the Mutation Research Centre in Melbourne, Australia, which became a leading center for the study of human mutation. He is the author of the book "Mutation Detection," a comprehensive resource on the subject, widely used by researchers and clinicians. This book covers a wide range of techniques for detecting mutations, including denaturing gradient gel electrophoresis (DGGE), single-strand conformation polymorphism (SSCP), chemical cleavage of mismatch (CCM), and heteroduplex analysis.

His research focused on improving the sensitivity and accuracy of these methods, as well as developing new approaches for mutation detection. He also made significant contributions to the understanding of the role of mutations in human disease. Cotton's work has had a major impact on the diagnosis and treatment of genetic disorders.

He also played a crucial role in advocating for open access to genetic information and promoting the ethical use of genetic technologies. His efforts helped to establish international standards for mutation detection and genetic testing.