MeT-5a

MeT-5a is a human mesothelioma cell line. It is derived from pleural fluid obtained from a patient with malignant mesothelioma. The MeT-5a cell line is considered non-tumorigenic and is often utilized as a control in in vitro experiments comparing it to malignant mesothelioma cell lines. Specifically, it is commonly used as a model of normal mesothelial cells, the cells that line the pleural, peritoneal, and pericardial cavities. Research using MeT-5a cells often investigates the differences in gene expression, protein production, and cellular behavior between normal and cancerous mesothelial cells, aiding in the understanding of mesothelioma development and potential therapeutic targets. This cell line provides a valuable tool for studying the biology of the mesothelium and the pathogenesis of mesothelioma in a controlled laboratory setting.