Etafenone

Etafenone is an antiarrhythmic drug used in the treatment of cardiac arrhythmias, particularly supraventricular and ventricular arrhythmias. It belongs to the Class IC antiarrhythmic agents, which means it works by blocking sodium channels in the heart, slowing the rate of depolarization and conduction velocity in the atria, ventricles, and His-Purkinje system. This action helps to stabilize the heart rhythm and prevent or terminate abnormal heartbeats.

Etafenone is often prescribed orally and is metabolized in the liver. Common side effects can include dizziness, blurred vision, gastrointestinal disturbances, and proarrhythmic effects (paradoxically causing or worsening arrhythmias). Due to its potential for proarrhythmic effects, it is typically reserved for patients with significant arrhythmias who have not responded to other treatments or for whom other treatments are not suitable. Regular monitoring of heart function, including ECGs, is essential during etafenone therapy. It should be used with caution in patients with pre-existing heart conditions or those taking other medications that affect heart rhythm.