Vesosome

A vesosome is a synthetic vesicle composed primarily of amphiphilic molecules. Unlike liposomes, which are typically composed of phospholipids, vesosomes can be constructed from a wider range of amphiphilic materials including block copolymers, surfactants, or combinations thereof. This broader range of building blocks allows for the tailoring of vesosome properties such as size, stability, permeability, and responsiveness to external stimuli.

Vesosomes are often designed to encapsulate and deliver therapeutic agents, imaging agents, or other functional molecules. The ability to precisely control the vesicle's composition and architecture makes them attractive for various applications in drug delivery, diagnostics, and materials science. The term 'vesosome' is frequently used in the fields of nanotechnology and pharmaceutical sciences to differentiate these synthetic vesicles from naturally occurring liposomes or exosomes. Compared to liposomes, vesosomes constructed from block copolymers, for example, often exhibit enhanced stability and prolonged circulation times in vivo. The morphology of vesosomes can also be manipulated to create structures such as polymersomes, which are typically characterized by thicker membranes and greater structural integrity. The selection of amphiphilic material will determine the vesosome's biocompatibility and biodegradability, further influencing its suitability for specific biomedical applications.