TPD52L2

TPD52L2 is a human gene. It belongs to the TPD52 (tumor protein D52) family of proteins, also known as the Norgen or Napa family. The TPD52 family is characterized by a highly conserved N-terminal coiled-coil domain and a less conserved C-terminal domain. There are three members in this family: TPD52, TPD52L1 (TPD52-like 1), and TPD52L2.

TPD52L2, also sometimes referred to as PCANAP3 (Prostate Cancer Associated NAPA Protein 3), encodes a protein whose function is not yet fully understood. While the specific biological role of TPD52L2 is still under investigation, research suggests it may be involved in protein trafficking, cell signaling, and potentially oncogenesis (cancer development).

The gene encoding TPD52L2 is located on human chromosome 17. Expression patterns of TPD52L2 have been observed in various tissues and cell types. Studies have indicated differential expression of TPD52L2 in certain cancers, suggesting a potential role in tumor progression or as a biomarker. However, further research is required to fully elucidate its precise functions and its significance in both normal cellular processes and disease states. Investigations into the interaction of TPD52L2 with other proteins may also provide further insights into its biological roles.