Phytosome

A phytosome is a patented technology used to enhance the bioavailability of plant-derived compounds (phytochemicals), particularly those that are lipophilic (fat-soluble) but poorly absorbed due to their large size or poor water solubility. The technology involves binding the standardized plant extract to phosphatidylcholine, a key building block of cell membranes.

Phosphatidylcholine, being both water-soluble (hydrophilic) and fat-soluble (lipophilic), acts as a carrier molecule, facilitating the passage of the phytochemical across the intestinal lining and into the bloodstream. This is achieved through a lipophilic complex that can be easily absorbed. The resulting complex resembles a cell, hence the name "phytosome" (phyto = plant, some = cell-like).

The primary advantage of the phytosome technology is improved absorption compared to traditional herbal extracts. This can lead to a more pronounced therapeutic effect with lower doses of the plant extract, potentially reducing the risk of side effects.

The phytosome process involves a chemical reaction that binds the plant extract's molecules to phosphatidylcholine molecules. The resulting compound is a more lipophilic and bioavailable form of the original extract. This process does not involve genetic modification.

Phytosomes have been studied for various herbal extracts, including milk thistle (silymarin), green tea (epigallocatechin gallate - EGCG), grape seed extract (proanthocyanidins), and curcumin (from turmeric). Clinical studies have suggested improved bioavailability and efficacy for these extracts when formulated as phytosomes compared to their standard forms.