ACTL6B

ACTL6B (Actin-Like 6B) is a gene in humans that encodes for an actin-related protein. These proteins share structural similarities with actin, a ubiquitous and highly conserved protein known for its role in forming microfilaments, which are crucial components of the cytoskeleton. However, actin-related proteins like ACTL6B often have specialized functions that differ from the canonical functions of actin.

The specific function of ACTL6B is not yet fully understood, but research suggests it plays a role in chromatin remodeling and gene regulation. It is believed to be a component of ATP-dependent chromatin remodeling complexes, which alter the structure of chromatin to regulate gene expression. Chromatin remodeling complexes are essential for various cellular processes, including DNA replication, DNA repair, and transcription.

ACTL6B is associated with several human diseases and conditions, including certain types of cancer. Aberrant expression or mutations in ACTL6B have been linked to altered cell growth, proliferation, and differentiation, highlighting its potential importance in maintaining normal cellular functions. Further research is ongoing to fully elucidate the precise mechanisms by which ACTL6B contributes to these diseases and to explore its potential as a therapeutic target.