7,N,N-TMT

7,N,N-TMT stands for 7-nitro-N,N-dimethyl-1,2,3-benzotriazol-1-ium tetrafluoroborate. It is a reagent used in organic chemistry, specifically as a coupling agent in peptide synthesis.

7,N,N-TMT is a benzotriazole-based reagent that activates carboxylic acids, allowing them to react with amines to form amide bonds. This process is crucial in the synthesis of peptides and other molecules containing amide linkages. The presence of the nitro group at the 7-position enhances the reactivity of the benzotriazolium core. The tetrafluoroborate counterion provides stability and solubility to the reagent.

This reagent offers advantages such as rapid reaction times and high yields in peptide coupling reactions.