William Shearer (immunologist)

William Shearer is an American physician and immunologist, best known for his research on pediatric AIDS and primary immunodeficiency diseases.

Shearer received his M.D. from St. Louis University School of Medicine and completed his residency in pediatrics at Baylor College of Medicine. He then completed a fellowship in immunology at the National Institutes of Health (NIH).

His research has focused on the pathogenesis of HIV infection in children, the development of the immune system, and the diagnosis and treatment of primary immunodeficiency diseases. He has made significant contributions to the understanding of how HIV affects children differently than adults, particularly regarding the rapid progression of the disease in infants. Shearer's work has been instrumental in the development of therapeutic strategies for children with HIV.

Shearer has also played a leading role in the diagnosis and treatment of primary immunodeficiency diseases, a group of genetic disorders that affect the immune system. He has been involved in the identification of new genetic defects causing immunodeficiency and has developed new diagnostic and therapeutic approaches for these disorders.

He has held faculty positions at Baylor College of Medicine and Texas Children's Hospital, where he directed the Pediatric Immunology Program. He has published numerous peer-reviewed articles in leading medical journals and has been recognized for his contributions to the field of immunology with numerous awards and honors.