Men's United States Open (squash) 2015

The Men's United States Open (squash) 2015 was a professional squash tournament that took place at Drexel University in Philadelphia, Pennsylvania from October 8th to October 17th, 2015. It was part of the 2015–16 PSA World Tour and was a PSA World Series event.

The tournament featured a 32-player draw with players from around the world competing for prize money and world ranking points. The defending champion was Mohamed El Shorbagy.

Grégory Gaultier won the tournament, defeating Omar Mosaad in the final. This victory marked Gaultier's first United States Open title. The tournament was notable for its intense matches and high level of competition. Notable players participating included Nick Matthew, Ramy Ashour, and Amr Shabana. The event attracted a large audience and was widely covered by squash media outlets.