USS Pratt may refer to one of two ships of the United States Navy:
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USS Pratt (DE-363), a John C. Butler-class destroyer escort, commissioned in 1944 and decommissioned in 1946. She was named after Ensign Kenneth M. Pratt, lost in action during the attack on Pearl Harbor.
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USS Harold E. Pratt (DE-319), a Edsall-class destroyer escort, commissioned in 1943 and decommissioned in 1946. She was named after Lieutenant Harold E. Pratt, killed in action during the Battle of Guadalcanal.