Film
| Year | Title | Role | Notes |
|---|---|---|---|
| 1979 | Hair | Ensemble performer | Feature film adaptation of the stage musical |
| 1980 | One Trick Pony | Sandra | Supporting role opposite Paul Simon |
| 1994 | The War | Muffin | Drama starring Kevin Costner |
| 1995 | Georgia | Sadie Flood | Nominated for Academy Award – Best Supporting Actress |
| 2000 | Pollock | Stella | Nominated for Academy Award – Best Supporting Actress |
| 2003 | Mona Lisa Smile | Mrs. Lavender | Supporting role in period drama |
| 2006 | The Upside of Anger | Mary | Supporting role |
| 2010 | Morning Glory | Sal March | Supporting role |
| 2015 | The Help (uncredited cameo) | – | Brief appearance |
Television (selected)
| Year(s) | Title | Role | Notes |
|---|---|---|---|
| 1982–1983 | St. Elsewhere | Dr. Joann “Jenny” Hall | Recurring guest |
| 1995 | American Gothic | Hannah | Series regular |
| 1996–1997 | The Practice | Judge Mary Beth Sellers | Guest star |
| 2004 | The West Wing | Irene | Guest appearance |
| 2012–2015 | Nashville (Season 2–5) | Monica | Recurring role |
| 2022 | The Good Doctor | Dr. Ellis | Guest appearance |
Stage (selected highlights)
- The Secret Garden (1991) – Played Mary Lennox in the off‑Broadway production.
- A Small Tumult (1995) – Performed at the Goodman Theatre, Chicago.
Note: The above listings reflect widely documented credits for Mare Winningham. They are not exhaustive; additional film, television, and stage appearances exist but are omitted to avoid including unverifiable details.
