- Final Fantasy – Over 173 million units sold worldwide across the main series, spin‑offs, and remakes (cumulative figure reported by Square Enix up to December 2022).
- Pokémon (core video‑game series) – More than 380 million units sold globally (Nintendo and The Pokémon Company figures, 2023). While the franchise includes various genres, the primary RPG titles (e.g., Pokémon Red/Blue, Sword & Shield) are classified as role‑playing games.
- Dragon Quest – Approximately 85 million units sold worldwide (official totals from Square Enix, 2023).
- Monster Hunter – Around 84 million units sold globally (Capcom financial reports, 2023). The series is commonly described as an action‑RPG.
- Kingdom Hearts – About 38 million units sold worldwide (Square Enix reports, 2022).
- Tales (including Tales of series) – Roughly 27 million units sold globally (Bandai Namco disclosures, 2022).
- Persona – Over 15 million units sold worldwide for the mainline entries (Atlus financial data, 2022).
- Shin Megami Tensei – Approximately 12 million units sold worldwide for the core series (Atlus data, 2022).
- Fire Emblem – Exceeds 10 million units sold globally (Nintendo reports, 2023).
- Xenoblade Chronicles – More than 6 million units sold worldwide (Nintendo financial statements, 2022).
Note: Sales figures represent cumulative worldwide shipments or sales reported by the respective publishers and are rounded to the nearest million where precise numbers are not publicly disclosed.