Laryngeal cyst

Definition
A laryngeal cyst is a benign, fluid‑filled sac that develops within the tissues of the larynx (voice box). It is typically lined by epithelium and may arise from obstruction of mucosal glands, congenital epithelial inclusions, or trauma‑related ductal blockage.

Overview
Laryngeal cysts are relatively uncommon lesions that can occur at any age but are most frequently diagnosed in children and young adults. They are usually asymptomatic when small; larger cysts may produce hoarseness, dysphonia, a sensation of a foreign body, dysphagia, or, in rare cases, airway obstruction. Diagnosis is primarily made through direct laryngoscopy or flexible fiberoptic endoscopy, which allows visualization of the cyst’s size, location, and effect on surrounding structures. Imaging studies such as computed tomography (CT) or magnetic resonance imaging (MRI) may be employed to assess deep or submucosal lesions. Management typically involves surgical removal—either by microlaryngoscopic excision, laser ablation, or cold‑steel instrumentation—often with a low recurrence rate when complete excision is achieved.

Etymology/Origin
The term combines “laryngeal,” derived from the Greek larynx (Λάρυγξ) meaning “voice box,” with “cyst,” from the Greek kystis meaning “bladder” or “sac.” Thus, “laryngeal cyst” literally denotes a sac‑like lesion of the larynx.

Characteristics

  • Location: Can be situated in the supraglottic region (e.g., vallecula, epiglottis), on the vocal folds (glottic), or in the subglottic area.
  • Size: Ranges from a few millimetres to several centimetres; size influences symptomatology.
  • Histology: Generally lined by respiratory epithelium (pseudostratified columnar) or squamous epithelium, containing mucus or serous fluid.
  • Classification:
    • Congenital cysts – arise from embryologic remnants such as ductal epithelium.
    • Acquired cysts – result from blockage of mucous glands, chronic irritation, or post‑surgical changes.
    • Specific types – include mucous retention cysts, saccular cysts, ductal cysts, and epidermoid cysts.
  • Clinical course: Most are benign with an excellent prognosis after excision; however, incomplete removal may lead to recurrence.

Related Topics

  • Vocal fold nodules and polyps
  • Laryngocele (air‑filled dilation of the saccular ventricle)
  • Laryngeal papillomatosis
  • Subglottic stenosis
  • Otolaryngology (ENT) surgical techniques
  • Airway obstruction in pediatric populations

All information presented reflects current medical literature and standard clinical understanding of laryngeal cysts.

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