John William O'Grady (May 19, 1898 – November 21, 1963) was an American professional football player who primarily played as a tackle in the National Football League (NFL) during the 1920s.
O'Grady's professional career included stints with multiple teams:
- Frankford Yellow Jackets: He was a member of the Yellow Jackets team that won the 1926 NFL Championship, a notable achievement in early NFL history.
- Pottsville Maroons
- Providence Steam Rollers
Known for his rugged play as a lineman, O'Grady contributed to the development and competition of early professional football. After his playing career, he remained involved in various capacities outside of professional sports.