Hadrianopolis was an ancient city located in the Roman province of Macedonia. Its precise location remains debated, with some scholars placing it near or identifying it with present-day Edessa, Greece. Other possibilities exist, as several cities in the Roman Empire were named Hadrianopolis in honor of the emperor Hadrian. The Macedonian Hadrianopolis would have been founded or significantly expanded during Hadrian's reign (117-138 CE).
Evidence of the city's existence primarily comes from historical texts, including Roman itineraries and geographical works. These sources offer limited details about its size, population, or importance relative to other Macedonian cities like Thessalonica or Philippi. Archaeological investigations in the potential locations have yielded some Roman-era artifacts, but a definitive identification of Hadrianopolis in Macedonia remains a challenge for historians and archaeologists. Further excavation and study are necessary to fully understand the city's role in the Roman province.