Diphenic acid

Definition: Diphenic acid, systematically known as 2,2'-biphenyldicarboxylic acid, is an organic compound with the molecular formula C₁₄H₁₀O₄. It consists of a biphenyl backbone with a carboxylic acid group attached to each of the two phenyl rings at the 2- and 2'-positions.

Overview: Diphenic acid is a member of the biphenyl dicarboxylic acid family. It is isomeric with other biphenyldicarboxylic acids such as 3,3'- and 4,4'-biphenyldicarboxylic acid. This compound is primarily used in research contexts, particularly in the study of coordination chemistry, polymer science, and crystal engineering due to its ability to act as a bridging ligand in metal-organic frameworks (MOFs). It may also serve as a precursor or building block in the synthesis of more complex organic molecules.

Etymology/Origin: The name "diphenic acid" is derived from "diphenyl," indicating the presence of two phenyl rings, and the suffix "-ic acid," denoting its carboxylic acid functionality. The term reflects the compound’s structural composition and functional groups.

Characteristics:

  • Molecular formula: C₁₄H₁₀O₄
  • Molecular weight: 242.23 g/mol
  • Appearance: Typically a white to off-white crystalline solid
  • Solubility: Sparingly soluble in water; more soluble in polar organic solvents such as ethanol, dimethylformamide (DMF), and dimethyl sulfoxide (DMSO)
  • Melting point: Reported values vary; approximately 240–245°C (with decomposition)
  • Structure: Features two ortho-substituted carboxylic acid groups on a biphenyl core, which can influence conformational flexibility due to steric hindrance

Related Topics:

  • Biphenyl compounds
  • Dicarboxylic acids
  • Metal-organic frameworks (MOFs)
  • Organic synthesis precursors
  • Crystal engineering
  • Ligand design in coordination chemistry

Diphenic acid is distinct from structurally similar compounds such as phthalic acid (benzene-1,2-dicarboxylic acid), although both contain ortho-positioned carboxyl groups. Its use in materials science stems from its rigid aromatic framework and bifunctional reactivity.

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