Alkan-1-ol dehydrogenase (acceptor) is the systematic name for an enzyme that catalyzes the following chemical reaction:
a primary alcohol + acceptor an aldehyde + reduced acceptor
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donors with other acceptors. Other names in common usage include primary alcohol dehydrogenase and long-chain-alcohol dehydrogenase.
This enzyme participates in various metabolic pathways, including the biodegradation of xenobiotics and fatty acid metabolism. The enzyme requires a suitable electron acceptor, which can vary depending on the specific organism and enzyme. Common acceptors include quinones and cytochrome c.
The enzyme exhibits specificity towards primary alcohols, particularly long-chain alcohols. The activity can vary based on the chain length and structure of the alcohol substrate.
The biological function of Alkan-1-ol dehydrogenase (acceptor) is to oxidize primary alcohols into their corresponding aldehydes. This oxidation is a key step in the metabolic breakdown or transformation of these alcohols. The aldehydes produced can then be further metabolized by other enzymes in the cell.
