The 1952–53 Luxembourg National Division was the 39th season of top-level association football in Luxembourg. The competition was contested by 12 teams, with each team playing the others twice, once at home and once away, for a total of 22 matches per club. FC Progrès Niedercorn won the championship, securing the first league title in the club's history.
The season comprised 132 matches in total, with 474 goals scored, averaging 3.59 goals per match. The highest-scoring match of the season was Union Luxembourg 3–8 National Schifflange.
Final League Standings
| Pos | Team | Pld | W | D | L | GF | GA | GD | Pts |
|---|---|---|---|---|---|---|---|---|---|
| 1 | FC Progrès Niedercorn | 22 | 13 | 6 | 3 | 52 | 32 | +20 | 32 |
| 2 | Jeunesse Esch | 22 | 13 | 5 | 4 | 41 | 24 | +17 | 31 |
| 3 | Stade Dudelange | 22 | 11 | 5 | 6 | 40 | 25 | +15 | 27 |
| 4 | FA Red Boys Differdange | 22 | 10 | 2 | 10 | 37 | 39 | −2 | 22 |
| 5 | CS Fola Esch | 22 | 10 | 2 | 10 | 25 | 31 | −6 | 22 |
| 6 | Union Luxembourg | 22 | 9 | 3 | 10 | 44 | 49 | −5 | 21 |
| 7 | FC Red Star Merl-Belair | 22 | 10 | 1 | 11 | 41 | 51 | −10 | 21 |
| 8 | National Schifflange | 22 | 8 | 4 | 10 | 46 | 39 | +7 | 20 |
| 9 | CA Spora Luxembourg | 22 | 9 | 0 | 13 | 44 | 42 | +2 | 18 |
| 10 | SC Tétange | 22 | 7 | 3 | 12 | 33 | 41 | −8 | 17 |
| 11 | Alliance Dudelange | 22 | 7 | 3 | 12 | 39 | 47 | −8 | 17 |
| 12 | Racing Rodange | 22 | 5 | 6 | 11 | 32 | 54 | −22 | 16 |
The defending champions, National Schifflange, finished in seventh place. The bottom-placed team was relegated directly, while the tenth- and eleventh-placed teams contested a relegation play-off to determine the second relegated side.